采用EEG、fMRI等认知神经科学技术,结合神经内分泌和外周生理指标,研究应激和应激荷尔蒙对人类行为的影响及其认知神经机制。同时把上述基础研究的成果进行实际的应用,研究特殊人群面对突发事件和长期压力状态的心理行为变化规律、应急应对能力和心理韧性的评估和干预工具等。
学习及工作经历
1988年9月- 1992年7月 南通卫校 医士专业(中专)
2003年9月-2008年7月 中国科学院心理研究所 认知神经科学专业 获博士学位
2008年8 月-2011年2月 中科院心理所助理研究员
2011年3 月-2016年10月 中科院心理所副研究员 博士生导师(2014年始)
2016年11 月-至今 深圳大学心理学院 教授,博士生导师(2018年始)
主要获奖及荣誉
1、2019年度广东省科学技术奖-自然科学二等奖,情绪与认知的相互影响及其脑机制,罗跃嘉、徐鹏飞、罗文波、古若雷、秦绍正、吴健辉、张丹丹等
2、2009年度江苏省科技进步奖二等奖, 认知功能的神经心理脑机制研究及认知障碍的诊疗评估。董选,罗跃嘉,王苏弘,任艳玲,吴健辉,邢伟,王乃弋
3、2010年获得中科院心理研究所优秀助理研究员称号和奖励
4、2012年度北京市科学技术奖三等奖,脑高级功能调节及干预的机制研究。 宋为群,罗跃嘉,刘超,吴健辉,吴东宇,杜博琪
5、2012年度华夏医学科技奖二等奖,脑高级功能调节与干预的机制研究。宋为群,罗跃嘉,吴健辉等
主持和参与的科研项目
1、语言、情绪与认知障碍的发育发展机制与评估研究(子课题负责人,2019年~ 2025年,深港脑科学创新研究院项目)
2、皮质醇觉醒反应预测脑功能(主持,2018年~ 2021年,国自然科学基金面上项目)
3、情绪特质的评估与干预技术研究“情绪特质评估的心理生理指标”(子课题负责人,2017年~ 2019年,中央**委**区)
4、慢性应激对情绪调节的影响(主持,2014年~ 2017年,国自然科学基金面上项目)
5、突发事件的群体心理反应特征、演化规律及管理干预(参与,2012年~ 2014年,国家自然科学基金重大研究计划重点支持项目)
6、想象对知觉的促进效应及其认知神经机制(主持,2010年~ 2012年,国自然青年科学基金项目)
发表的主要研究论文
1.Yi W, Chen Y, Yan L, Kohn N, Wu J*. (2023). Acute stress selectively blunts reward anticipation but not consumption: An ERP study. Neurobiology of Stress 27: 100583.
2.Ding X, Zheng L, Liu Y, Zhang W, Wang N, Duan H*, Wu J*. (2023). Parenting styles and psychological resilience: The mediating role of error monitoring. Biological psychology 180: 108587.
3.Wu J, Liu Y, Zhang L, Wang N, Kohn N, Duan H*. (2023). Integrating the pattern of negative emotion processing and acute stress response with childhood stress among healthy young adults. Stress. 26(1):2195503.
4.Ding X, Zheng L, Wu J, Liu Y, Fang H, Xin Y, Duan H*. (2023). Performance monitoring moderates the relationship between stress and negative affect in response to an exam stressor. Int J Psychophysiol. 185:11-18.
5.Yan L, Kohn N, Yi W, Wang N, Duan H*, Wu J*. (2023). Blunted reward responsiveness prospectively predicts emotional distress when exposed to a naturalistic stressor. British Journal of Psychology 114(2):376-392.
6.Liu Y, Peng H, Wu J, Wang N, Duan H*. (2022). Linking Mild Childhood Adversity with Conflict and False Feedback Monitoring. Dev Neuropsychol. 47(7):353-368.
7.Chen Y, Yao Z#, Wang N, Wu J, Xin Y*. (2022). Adaption and validation of the Perceived Control of Internal States Scale (PCOISS) in Chinese adults: a cross-sectional study. BMC Psychol. 10(1):290.
8.Ding, X., Fang, H., Liu, Y., Zheng, L., Zhu, X., Duan, H*., & Wu, J*. (2022). Neurocognitive correlates of psychological resilience: Event-related potential studies. Journal of Affective Disorders, 312: 100-106
9.Liu, L., Wu J#., Geng H., Liu C., Luo Y., Luo J., Qin S*. (2021). Long-Term Stress and Trait Anxiety Affect Brain Network Balance in Dynamic Cognitive Computations. Cerebral Cortex. bhab393
10.Xiong, B., Chen, C., Tian, Y., Zhang, S., Liu, C., Evans, T. M., Fernandez, G., Wu, J., & Qin, S. (2021). Brain preparedness: The proactive role of the cortisol awakening response in hippocampal-prefrontal functional interactions. Prog Neurobiol 205: 102-127.
11.Shi, X., Nie, X., Wu, J. (2021). The cortisol awakening response and the late positive potentials evoked by unpleasant emotional pictures in healthy adults. Stress: 1-8. https://doi.org/10.1080/10253890.2021.2008902
12.Ma, Y., Peng H., Liu H., Gu, R., Peng, X., Wu, J.(2021). Alpha Frontal Asymmetry Underlies Individual Differences in Reactivity to Acute Psychosocial Stress, Psychophysiology, 58(10):e13893
13.Wu, J., Liu, Y., Fang H., Qin S., Nils, K., Duan, H*. (2021). The Relationship Between Childhood Stress and Distinct Stages of Dynamic Behavior Monitoring in Adults: Neural and Behavioral Correlates,Social Cognitive and Affective Neuroscience, 1-13.
14.Shi, X*., Wu, J*., Smyth, N. (2021). An inverted U-shaped relationship between cortisol awakening response and same-day error monitoring function in healthy males. Biological Psychology, 160, 108052.
15.Duan, H., Yan, L., Ding, X., Gan, Y., Kohn, N., & Wu, J*. (2020). Impact of the COVID-19 pandemic on mental health in the general Chinese population: Changes, predictors and psychosocial correlates. Psychiatry Research, 113396.
16.Yan, L., Gan, Y., Ding, X., Wu, J., & Duan, H. (2020). The relationship between perceived stress and emotional distress during the COVID-19 outbreak: Effects of boredom proneness and coping style. Journal of Anxiety Disorders, 102328.
17.Gan, Y., Ma, J., Wu, J. , Chen, Y., Zhu, H., & Hall, B. J. (2020).Immediate and Delayed Psychological Effects of Province-wide Lockdown and Personal Quarantine during the COVID-19 Outbreak in China. Psychological Medicine,1-12, Online ahead of print.
18.Cao, C., Wang, L*., Wu, J*., Bi, Y., Yang, H., Fang, R., . . . Hall, B. J. (2020). A comparison of ICD-11 and DSM-5 criteria for PTSD among a representative sample of Chinese earthquake survivors. Eur J Psychotraumatol, 11(1), 1760481.
19.Shi, X., & Wu, J. (2020). Chronic stress and anticipatory event-related potentials: the moderating role of resilience. Stress, 1-7.
20.Lin, L., Wu, J., Yuan, Y., Sun, X., & Zhang, L. (2020). Working Memory Predicts Hypothalamus-Pituitary-Adrenal Axis Response to Psychosocial Stress in Males. Front Psychiatry, 11, 142. doi:10.3389/fpsyt.2020.00142
21.Xin, Y., Yao, Z., Wang, W., Luo, Y., Aleman, A., &Wu, J*. (2020). Recent life stress predicts blunted acute stress response and the role of executive control. Stress, 1-23.
22.Cao, C., Wang, L*., Wu, J*., Li, G., Fang, R., Liu, P., . . . Elhai, J. D. (2019). Association between the OXTR rs53576 genotype and latent profiles of post-traumatic stress disorder and depression symptoms in a representative sample of earthquake survivors. Anxiety, Stress, & Coping, 1-8.
23.Shi, X., Sun, X., Yao, Z., Yuan, Y., Wu, J.*, &Clow, A. (2018). The cortisol awakening response predicts response inhibition in the afternoon of the same day. Psychoneuroendocrinology, 89, 23-29.
24.Wu J, Sun X, Wang L, Zhang L, Fernandez G, &Yao Z*. (2017). Error consciousness predicts physiological response to an acute psychosocial stressor in men. Psychoneuroendocrinology, 83, 84-90.
25.Liu, Y., Lin, W., Liu, C., Luo, Y., Wu, J.*, Bayley, P. J., & Qin, S.* (2016). Memory consolidation reconfigures neural pathways involved in the suppression of emotional memories. Nature Communications, 7, 13375.
26.Zhang L, Qin S, Yao Z, Zhang K, Wu J*. (2016). Long-term academic stress enhances early processing of facial expressions. Int J Psychophysiol, 109, 138-146.
27.Duan, H., Wang, L., Fernández, G., Zhang, K., Wu, J*. (2016). Increased anticipatory contingent negative variation in posttraumatic stress disorder. Biological Psychology, 17:80-88.
28.Fu Q*., Liu Y., Dienes Z., Wu J., Chen W, Fu X. (2016). The role of edge-based and surface-based information in natural scene categorization: Evidence from behavior and event-related potentials. Consciousness and Cognition, 43, 152-166.
29.Wu, J., Zhang, S., Li, W., Qin, S., He, Y., Yang, Z., . . . Zhang, K*. (2015). Cortisol awakening response predicts intrinsic functional connectivity of the medial prefrontal cortex in the afternoon of the same day. Neuroimage, 122, 158-165.
30.Zhang, L., Duan, H., Qin, S., Yuan, Y., Buchanan, T. W., Zhang, K., &Wu, J*. (2015). High cortisol awakening response is associated with impaired error monitoring and decreased post-error adjustment. Stress, 18(5), 561-568.
31.Duan, H., Yuan, Y., Yang, C., Zhang, L., Zhang, K., &Wu, J*. (2015). Anticipatory processes under academic stress: an ERP study. Brain Cogn, 94, 60-67.
32.Ma, H., Wang, Y*.,Wu, J., Liu, H., Luo, P., & Han, B. (2015). Overactive Performance Monitoring Resulting from Chronic Exposure to High Altitude. Aerosp Med Hum Perform, 86(10), 860-864.
33.Yuan, Y., Wu, J., & Zhang, K*. (2014). Long-Term Psychosocial Stress Attenuates Attention Resource of Post-Error. Engineering Psychology and Cognitive Ergonomics, Epce 2014, 8532, 114-122.
34.Wu, J., Yuan, Y., Duan, H., Qin, S., Buchanan, T. W., Zhang, K., & Zhang, L*. (2014). Long-term academic stress increases the late component of error processing: an ERP study. Biol Psychol, 99, 77-82.
35.Duan, H., Yuan, Y., Zhang, L., Qin, S., Zhang, K., Buchanan, T. W., &Wu, J*. (2013). Chronic stress exposure decreases the cortisol awakening response in healthy young men. Stress, 16(6), 630-637.
36.Wu, J*.,Duan, H., Tian, X., Wang, P., & Zhang, K. (2012). The effects of visual imagery on face identification: an ERP study. Front Hum Neurosci, 6, 305.
37.Ou, B., Wu, C*., Zhao, G., &Wu, J. (2012). P300 amplitude reflects individual differences of navigation performance in a driving task. International Journal of Industrial Ergonomics, 42(1), 8-16.
38.Wu, J., Yu, Z., Mai, X., Wei, J., & Luo, Y*. (2011). Pitch and loudness information encoded in auditory imagery as revealed by event-related potentials. Psychophysiology, 48(3), 415-419.
39.Ge, Y., Wu, J., Sun, X., & Zhang, K*. (2011). Enhanced mismatch negativity in adolescents with posttraumatic stress disorder (PTSD). Int J Psychophysiol, 79(2), 231-235.
40.Wu, J., Mai, X., Yu, Z., Qin, S., & Luo, Y*. (2010). Effects of discrepancy between imagined and perceived sounds on the N2 component of the event-related potential. Psychophysiology, 47(2), 289-298.
41.Wu, J., Ge, Y., Shi, Z., Duan, X., Wang, L., Sun, X., & Zhang, K*. (2010). Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: a combined behavioral and ERP study. Neurosci Lett, 486(3), 117-121.
42.Wang, Y., Wu, J., Fu, S., & Luo, Y*. (2010). Orienting and focusing in voluntary and involuntary visuospatial attention conditions: an event-related potential study. Journal of Psychophysiology, 24:198-209.
43.Huang, Z., Zhang, J., Yang, Z*., Dong, G., Wu, J., Chan, A., &Weng, X. (2010). Verbal memory retrieval engages visual cortex in musicians. Neuroscience, 168(1), 179-189.
44.Duan, X., Shi, J*.,Wu, J., Mou, Y., Cui, H., & Wang, G. (2009). Electrophysiological correlates for response inhibition in intellectually gifted children: a Go/NoGo study. NeurosciLett, 457(1), 45-48.
45.Wu, J., Mai, X., Chan, C. C., Zheng, Y., & Luo, Y*. (2006). Event-related potentials during mental imagery of animal sounds. Psychophysiology, 43(6), 592-597.
46.Mai, X., Luo, J*.,Wu, J., & Luo, Y*. (2004). "Aha!" effects in a guessing riddle task: an event-related potential study. Hum Brain Mapp, 22(4), 261-270.
47.彭惠妮,吴健辉,孙小方,关青,罗跃嘉.特质焦虑对急性心理性应激反应的预测.(2018)心理学报,50(9), 997-1006。
48.罗跃嘉,林婉君,吴健辉,秦绍正*. (2013).应激的认知神经科学研究进展.生理科学进展.44(5): 345-353.
49.吴健辉,罗跃嘉*.(2005).盲人的跨感觉通道重组.心理科学进展, 13: 406-412.
50.罗跃嘉*,吴健辉.(2005).情绪的心理控制与认知研究策略.西南师范大学学报(人文社会科学版), 31: 26-29.
发明专利授权
一种脑状态监测与调控装置、方法、处理器及终端设备,专利号:ZL201910854634.6,申请人:深圳大学,发明人:吴健辉,彭小虎,唐山。
教学工作
主讲心理学院本科生“应激心理学”
(招聘博士后1-2位、应激心理学方向博士优先,欢迎志趣相投来投简历等)